Tesofensine
Tesofensine is a weight
loss drug still being put through testing phases. Its developers are NeuroSearch
based out of Denmark. It started its testing and development later than those
of Qnexa, Lorcaserin and Contrave. As a result it still at the time of this
writing has not entered into phase three testing to our knowledge. Phase three
testing is very in-depth usually lasting about one year's time and with possibly
thousands of people involved. If all goes well, it would still be at least
one to two years before it was submitted to the FDA. Tesofensine was first being
developed to treat Parkinson's and Alzheimer's disease but was resulting in poor
results for their treatment. But during the testing it was found that Tesofensine
was really producing great results in weight loss. This is what caused the
discovery and development as Tesofensine as a weight loss drug. Test results
out have Tesofensine beating out the results of Sibutramine (A current anti-obesity
drug) by double the weight loss.
A benefit shared with that of Lorcaserin is that a study showed
that Tesofensine has a very low change of abuse or be taken for recreational
purposes. If this stat holds true over any phase three testing and continues
to work twice as well as Sibutramine it could be one of the biggest players in
the weight loss drug field. Over a 6 month testing phase patients where found
to lose an average of 10.6% of there body mass. Those who merely took half of
this still lost an average of 9.6% of their weight. Side effects reported have
been mid to moderate levels of insomnia, dry mouth, constipation and some gastrointestinal
tract issues but nothing too serious and not found with all takers.
So far there is not a lot to report on Tesofensine as it still needs further testing
to give its argument strength. But this one could hold a lot of potential.
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